Steered Molecular Dynamics Simulations Predict Conformational Stability of Glutamate Receptors
نویسندگان
چکیده
منابع مشابه
Steered Molecular Dynamics Simulations Predict Conformational Stability of Glutamate Receptors
The stability of protein-protein interfaces can be essential for protein function. For ionotropic glutamate receptors, a family of ligand-gated ion channels vital for normal function of the central nervous system, such an interface exists between the extracellular ligand binding domains (LBDs). In the full-length protein, the LBDs are arranged as a dimer of dimers. Agonist binding to the LBDs o...
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ژورنال
عنوان ژورنال: Journal of Chemical Information and Modeling
سال: 2016
ISSN: 1549-9596,1549-960X
DOI: 10.1021/acs.jcim.6b00297